News

The list below is an archive of "Latest News".

2018

September 2018, Promotion: Dr. Nick Seyfried promoted to Associate Professor. Congratulations, Nick!

June 2018, New Publication: Dr. Srikant Rangaraju's paper titled, Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins, is published in Molecular Neurodegeneration. Jun 28;13(1):34.

May 2018, Thesis Defense: BCDB graduate student Isaac Bishof successfully defended his PhD thesis. Congrats Dr. Bishof!

May 2018, paper accepted: Isaac’s paper titled “RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease” was recently accepted for publication by the Journal of Biological Chemistry.

March, 2018, conference presentation: Nick presented a talk titled “Integrative Proteomics for Novel Target and Biomarker Discovery in Alzheimer’s Disease” at the National Institutes of Health (NIH) Alzheimer’s Disease Research Summit in Bethesda Maryland. Click link above to see Nick’s talk at the 4:21:00 mark.

March 2018, paper accepted: Lingyan’s paper titled “Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease” was recently accepted for publication by the Scientific Data.

2017

November 2017, Paper Accepted: Mfon’s paper titled, “A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain,” was accepted for publication to the EMBO Molecular Medicine. This work was done in collaboration with Jonathan Glass (Emory Neurology), Director of the Emory ALS Clinic. 

September 2017, Paper AcceptedIan’s paper titled, “Generation of Clickable Pittsburgh Compound B for the Detection and Capture of β-Amyloid in Alzheimer's Disease Brain” was accepted for publication at Bioconjugate Chemistry. This work was done in collaboration with Lary Walker (Emory Neurology). 

August 2017,  Press Release: Excellent summary of our new GenPro software by Genomeweb, “Emory Team Develops New Software for Building Sample-Specific Mass Spec Reference Databases”. 

August 2017, Paper Review: GenPro is highlighted on Ben Orsburn’s blog, “GenPro -- 1 step closer to personalized proteomics!”.

July 2017, Press Release: Our research on Alzheimer’s Disease protein networks was highlighted in an article on Alzforum titled, "Alzheimer’s Proteomics Treasure Trove?"

July 2017, Conference Presentation: Nick co-chaired and presented a talk in the Protein-Protein Interactions Session at the Alzheimer’s Association International Conference (AAIC) in London, England. 

July 2017 Paper Accepted: Our paper titled, “Integrating Next-Generation Genomic Sequencing and Mass Spectrometry to Estimate Allele-Specific Protein Abundance in Human Brain,” was accepted for publication to the Journal of Proteome Research. This work was done in collaboration with Thomas Wingo (Emory Neurology), who developed the GenPro software. 

June 2017, Conference Presentation:  Nick Presented at talk titled, “Protein co-expression network analysis of asymptomatic Alzheimer’s disease” at the EMBO | EMBL Symposia on Mechanisms in Neurodegeneration in Heidelberg Germany

March 2017, Conference Presentation: Nick Presented at talk titled, “A Multi-Network Approach to Define Pathways Altered in Alzheimer’s Disease and Parkinson’s Disease” at the US HUPO meeting in San Diego, CA. 

March 2017, Travel Award: Congratulations to Isaac Bishof who was awarded a Travel Grant for his attendance at the 2017 RNA Society meeting in Prague to present a poster titled, “A Network Approach Reveals Novel Roles of Low Complexity Domains in Spliceosomal Proteins”. 

January 2017, Grant News: Nick, Dean Jones and Eric Ortlund were awarded a $13.5 grant from the NIH to serve as a site for the Molecular Transducers of Physical Activity in Humans Program. This work will also be conducted in collaboration with GaTech. Click here to read Emory News Center press release. 

2016

December 2016, press release: Alzheimer's Researchers Identify Protein Co-Expression Networks Linked to Disease” highlights the findings of our new Cell Systems Paper.

December 2016, press release: Alzheimer's: Proteomics gives clues toward alternatives to amyloid” highlights the findings of our newCell Systems Paper.

December 2016, paper accepted: Our paper titled “A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease” was recently accepted for publication by Cell Systems

October 2016, paper accepted: Our paper titled “Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer’s Disease progression” was recently accepted for publication by Proteomics.

September 2016, grant news: Our R01 proposal titled “Tau-Spliceosome Interactions in Alzheimer's Disease” was recently funded by the National Institute on Aging (NIA). This work is being done in collaboration with Dr. Josh Shulman at Baylor College of Medicine.

September 2016, Fellowship award, Congratulations to Srikant Rangaraju from being awarded a NIH K08 fellowship titled, “Microglial and macrophage potassium channels as regulators of neuroinflammation in Alzheimer's Disease”. Nick is serving as co-mentor.

July, 2016, conference presentation: Nick presented a talk titled “Proteomic network analysis to find common mechanisms underlying Alzheimer’s and Parkinson’s Disease” at the Alzheimer’s Association International Conference (AAIC) in Toronto, Canada.

June 2016, conference presentation: Isaac Bishof presented his poster titled “Identification of methylation and phosphorylation in arginine/serine rich domains by electron transfer dissociation” at the American Society for Mass Spectrometry (ASMS) meeting in San Antonio, Texas.

June 2016, conference presentation: Nick presented a poster titled “A Network Based Approach to Understand the Brain Proteome in Alzheimer’s Disease” at the American Society for Mass Spectrometry (ASMS) meeting in San Antonio, Texas.

May 2016, Fellowship Award, Congratulations to Isaac Bishof (BCDB program) for being awarded a Ruth L. Kirschstein National Research Service Award (NRSA) F31 Fellowship titled “Defining Mechanisms of RNA-Binding Protein Assembly Linked to Alzheimer’s Disease”

March 2016, Conference Presentation: Nick Presented at talk titled “Protein Co-Expression Network Analysis Reveals Cell Type Changes Linked to Alzheimer's Disease” at the US HUPO meeting in Boston, Massachusetts.

2015

November 2015, grant news, Our Biomarkers Across Neurodegenerative Diseases (BAND) proposal was funded by the Alzheimer’s Association, Michael J. Fox Foundation, Weston Brain Institute and Alzheimer’s Research UK. Learn more here:  http://www.alz.org/research/alzheimers_grants/BAND/overview-2016.asp?BAND=2016seyf

March 2015, Travel Award: Congratulations to Isaac Bishof who was awarded a Travel Grant for his attendance at the 2015 ASBMB meeting to present a poster on his work on the intrinsically disordered low complexity domains in the RNA-binding protein U1-70K.  

January 2015, Paper Accepted: Eric’s paper on the quantitative phosphoproteome analysis of Alzheimer’s Disease postmortem brain tissue was published in Proteomics.

2014

December 2014, Paper Accepted: Ian’s paper on the aggregation properties of U1-70K was published in the Journal of Biological Chemistry.