• Uncovering the Molecular Mechanisms Driving Transcription

  • Protein Dynamics

  • Molecular Evolution

  • Phospholipid Signaling


Eric A. Ortlund, Ph.D.
Associate Professor
Department of Biochemistry
1510 Clifton Rd. NE
Atlanta, GA 30322

O. Wayne Rollins Center
G235 Office/Lab
404.727.5014 (Office tel.)
404.727.2563 (Lab tel.)
404.727.2738 (Fax)

Ortlund Google Scholar

Ortlund Pubmed

Welcome to the Ortlund Lab

We use sophisticated structural biology techniques such as x-ray crystallography and mass spectrometry coupled with an array of biochemical techniques to gain a molecular level understanding of transcriptional signaling - with a particular focus on lipid mediated signaling and transport. We currently pursue structural and biochemical studies of human nuclear receptors, which are lipid regulated transcription factors that play central roles in development, cancer, stress and metabolism. We have also made seminal contributions to the field of molecular evolution using nuclear receptors as a model system to study how tight molecular partnerships evolve.

Latest News

January 2017, New Lab Baby!  Emily Rye Weikum and her husband welcomed a baby boy on January 10th, 2017. Welcome to the lab, Kellan Weikum! 

January 2017, Travel Award. Dr. Denise Okafor was awarded a travel award to attend this years ASBMB conference in Chicago, Illinois. 

January 2017, New Grant. Congratulations to Dr. Eric Ortlund for being awarded a $13.6M grant in collaboration with Georgia Tech to study lipidomic changes as a result of exercise! MoTrPAC

January 2017, Selected Speaker. Dr. Denise Okafor was selected to give a talk for FIRST postdocs at Emory University. 

December 2017, New Lab Baby! Dr. Filipp Frank and his wife welcomed a baby boy on December 30th, 2016. Welcome to the lab, Leon Frank! 

Emory Lipidomics Core

Lipidomics Core ImageThe Emory Integrated Lipidomics Core (EILC), a member core of the Emory Integrated Core Facilities (EICF), provides quantitative lipid analytical services using cutting-edge mass spectrometry methods to both clinical and basic biomedical research efforts at Emory.

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