• Uncovering the Molecular Mechanisms Driving Transcription

  • Protein Dynamics

  • Molecular Evolution

  • Phospholipid Signaling


Eric A. Ortlund, Ph.D.
Associate Professor
Department of Biochemistry
1510 Clifton Rd. NE
Atlanta, GA 30322

O. Wayne Rollins Center
G235 Office/Lab
404.727.5014 (Office tel.)
404.727.2563 (Lab tel.)
404.727.2738 (Fax)

Ortlund Google Scholar

Ortlund Pubmed

Welcome to the Ortlund Lab

We use sophisticated structural biology techniques such as x-ray crystallography and mass spectrometry coupled with an array of biochemical techniques to gain a molecular level understanding of transcriptional signaling - with a particular focus on lipid mediated signaling and transport. We currently pursue structural and biochemical studies of human nuclear receptors, which are lipid regulated transcription factors that play central roles in development, cancer, stress and metabolism. We have also made seminal contributions to the field of molecular evolution using nuclear receptors as a model system to study how tight molecular partnerships evolve.

Latest News

June 2017, New Grant. Congratulations to Dr. Xu Liu on being awarded an AHA Fellowship. 

May 2017, Selected Speaker. Congratulations to Suzanne Mays, who was selected as a speaker at this years American Crystallography Association Conference in New Orleans, LA. 

May 2017, New Lab Member. Welcome to Emma D'Agostino, newest member of the Ortlund Lab and a second year BCDB student. 

May 2017, Ph.D. Defense. Congratulations to Dr. Emily Rye Weikum on successfully defending her PhD thesis! 

April 2017, Selected Presentation. Congratulations to Dr. Denise Okafor on being selected to present a poster at the 2017 ASBMB Conference.

Emory Lipidomics Core

Lipidomics Core ImageThe Emory Integrated Lipidomics Core (EILC), a member core of the Emory Integrated Core Facilities (EICF), provides quantitative lipid analytical services using cutting-edge mass spectrometry methods to both clinical and basic biomedical research efforts at Emory.

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