• rRNA modification by the thiostrepton-resistance methyltransferase (Tsr)

  • Molecular mechanisms of RNA-mediated regulation of OAS1

  • Structural studies of aminoglycoside-resistance rRNA methyltransferases


Graeme L. Conn, Ph.D.
Associate Professor
Department of Biochemistry
O. Wayne Rollins Rsch. Center
1510 Clifton Rd. NE
Atlanta, GA 30322

4135 Office
4178 Lab
404.727.5965 (Office tel.)
404.712.0058 (Lab tel.)
404.727.2738 (Fax)

Research Gate


We use modern biochemical and biophysical methods to study the structures, interactions and biological functions of biomedically important RNA and protein molecules. Current topics include mechanisms of bacterial antibiotic resistance that arise through ribosomal RNA modification and non-coding RNA-mediated pathogen evasion of host cell innate immune responses.

Interested in joining the Conn Lab? We currently have an opening for a Postdoctoral fellow with experience in protein biochemistry and/ or X-ray crystallography (see here for details).


Our research is currently funded by NIH/NIAID grant R01-AI088025.

Research Highlights

Emily Kuiper award

Congratulations to Emily Kuiper who defended her PhD thesis in July 2016! Emily is pictured below with former Graduate Division Director Dr. Keith Wilkinson receiving her award for the BCDB Graduate Program Scholar of the Year for 2015.

Brenda Calderon

Congratulations to Brenda Calderon who received a 3-year Achievement Reward for College Students (ARCS) Award in August 2015. Brenda (right) is pictured at a recent ARCS Foundation event with her sponsor Mrs. Jane Dolinger.

Latest News

  • January 2017, Paper Accepted: Brenda Calderon’s paper on the human non-coding RNA 886 (nc886) and PKR is accepted for publication in RNA. Congrats Brenda!
  • December 2016, Paper Accepted: A paper on the Mycobacterium tuberculosis methyltransferase TlyA by former lab members and co-first authors Emily Kuper and Marta Witek is accepted for publication in J. Biol. Chem.
  • December 2016, Moving On: Dr. Emily Kuiper leaves the lab to start her postdoctoral fellowship with Dr. Wayne A. Marasco’s group at the Dana Farber Cancer Institute. Good luck Emily!
  • November 2016, Thesis Defense: MMG graduate student Kellie Vinal successfully defended her PhD thesis. Congratulations Dr. Vinal!
  • November 2016, New Lab Member: BCDB student Zane Laughlin joins the lab for one of his BCDB Program rotations. Welcome Zane!
  • September 2016, New Lab Member: BCDB student Becca Giuntoli joins the lab for one of her BCDB Program rotations. Welcome Becca!
  • July 2016, New Publication: Graeme’s paper with BCDB faculty colleagues describing the Program’s scientific writing course is published in Traffic!
  • July 2016, New Award: Graduate student Sam Schwartz is appointed to the BCDB Program’s NIH T32 training grant. Congrats Sam!
  • July 2016, Thesis Defense: BCDB graduate student Emily Kuiper successfully defended her PhD thesis. Congratulations Dr. Kuiper!