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Tomic TI, Moric I, Conn GL, Vasiljevic B. Aminoglycoside resistance genes sgm and kgmB protect bacterial but not yeast small ribosomal subunits in vitro despite high conservation of the rRNA A-site. Res Microbiol. 2008 Nov-Dec;159(9-10):658-62. doi: 10.1016/j.resmic.2008.09.006. Epub 2008 Oct 1. PubMed PMID: 18930134; PubMed Central PMCID: PMC2791848.
Savic M, Ilic-Tomic T, Macmaster R, Vasiljevic B, Conn GL. Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm. J Bacteriol. 2008 Sep;190(17):5855-61. doi: 10.1128/JB.00076-08. Epub 2008 Jun 27. PubMed PMID: 18586937; PubMed Central PMCID: PMC2519519.
Wahid AM, Coventry VK, Conn GL. Systematic deletion of the adenovirus-associated RNAI terminal stem reveals a surprisingly active RNA inhibitor of double-stranded RNA-activated protein kinase. J Biol Chem. 2008 Jun 20;283(25):17485-93. doi: 10.1074/jbc.M802300200. Epub 2008 Apr 22. PubMed PMID: 18430723; PubMed Central PMCID: PMC2427366.
Coventry VK, Conn GL. Analysis of adenovirus VA RNAI structure and stability using compensatory base pair modifications. Nucleic Acids Res. 2008 Mar;36(5):1645-53. doi: 10.1093/nar/gkn020. Epub 2008 Feb 3. PubMed PMID: 18250084; PubMed Central PMCID: PMC2275154.
Dunham CM, Conn GL. Recombinant RNA expression. Nat Methods. 2007 Jul;4(7):547-8. doi: 10.1038/nmeth0707-547. PubMed PMID: 17599081.
Hobro AJ, Rouhi M, Blanch EW, Conn GL. Raman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES. Nucleic Acids Res. 2007;35(4):1169-77. doi: 10.1093/nar/gkm012. Epub 2007 Jan 30. PubMed PMID: 17264119; PubMed Central PMCID: PMC1851652.
Nie Y, Hobbs JR, Vigues S, Olson WJ, Conn GL, Munger SD. Expression and purification of functional ligand-binding domains of T1R3 taste receptors. Chem Senses. 2006 Jul;31(6):505-13. doi: 10.1093/chemse/bjj053. Epub 2006 Apr 18. PubMed PMID: 16621970.
Maeder C, Conn GL, Draper DE. Optimization of a ribosomal structural domain by natural selection. Biochemistry. 2006 May 30;45(21):6635-43. doi: 10.1021/bi052544p. PubMed PMID: 16716074; PubMed Central PMCID: PMC2698295.
Nie Y, Vigues S, Hobbs JR, Conn GL, Munger SD. Distinct contributions of T1R2 and T1R3 taste receptor subunits to the detection of sweet stimuli. Curr Biol. 2005 Nov 8;15(21):1948-52. doi: 10.1016/j.cub.2005.09.037. PubMed PMID: 16271873.
Dunstan MS, Guhathakurta D, Draper DE, Conn GL. Coevolution of protein and RNA structures within a highly conserved ribosomal domain. Chem Biol. 2005 Feb;12(2):201-6. doi: 10.1016/j.chembiol.2004.11.019. PubMed PMID: 15734647.
Phelan M, Banks RJ, Conn G, Ramesh V. NMR studies of the structure and Mg2+ binding properties of a conserved RNA motif of EMCV picornavirus IRES element. Nucleic Acids Res. 2004;32(16):4715-24. doi: 10.1093/nar/gkh805. Print 2004. PubMed PMID: 15353559; PubMed Central PMCID: PMC519103.
Clark AT, Robertson ME, Conn GL, Belsham GJ. Conserved nucleotides within the J domain of the encephalomyocarditis virus internal ribosome entry site are required for activity and for interaction with eIF4G. J Virol. 2003 Dec;77(23):12441-9. doi: 10.1128/jvi.77.23.12441-12449.2003. PubMed PMID: 14610168; PubMed Central PMCID: PMC262551.
Conn GL. Expression of active RNA-activated protein kinase (PKR) in bacteria. Biotechniques. 2003 Oct;35(4):682-4, 686. doi: 10.2144/03354bm03. PubMed PMID: 14579730.
Walker SC, Avis JM, Conn GL. General plasmids for producing RNA in vitro transcripts with homogeneous ends. Nucleic Acids Res. 2003 Aug 1;31(15):e82. doi: 10.1093/nar/gng082. PubMed PMID: 12888534; PubMed Central PMCID: PMC169970.
Gyi JI, Gao D, Conn GL, Trent JO, Brown T, Lane AN. The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications. Nucleic Acids Res. 2003 May 15;31(10):2683-93. doi: 10.1093/nar/gkg356. PubMed PMID: 12736318; PubMed Central PMCID: PMC156038.
Conn GL, Gittis AG, Lattman EE, Misra VK, Draper DE. A compact RNA tertiary structure contains a buried backbone-K+ complex. J Mol Biol. 2002 May 10;318(4):963-73. doi: 10.1016/S0022-2836(02)00147-X. PubMed PMID: 12054794.
Conn GL, Draper DE, Lattman EE, Gittis AG. Crystal structure of a conserved ribosomal protein-RNA complex. Science. 1999 May 14;284(5417):1171-4. doi: 10.1126/science.284.5417.1171. PubMed PMID: 10325228.
Conn GL, Brown T, Leonard GA. The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solution. Nucleic Acids Res. 1999 Jan 15;27(2):555-61. doi: 10.1093/nar/27.2.555. PubMed PMID: 9862980; PubMed Central PMCID: PMC148215.
Conn GL, Gutell RR, Draper DE. A functional ribosomal RNA tertiary structure involves a base triple interaction. Biochemistry. 1998 Aug 25;37(34):11980-8. doi: 10.1021/bi980825+. PubMed PMID: 9718323.
Gyi JI, Lane AN, Conn GL, Brown T. The orientation and dynamics of the C2'-OH and hydration of RNA and DNA.RNA hybrids. Nucleic Acids Res. 1998 Jul 1;26(13):3104-10. doi: 10.1093/nar/26.13.3104. PubMed PMID: 9628906; PubMed Central PMCID: PMC147665.
Conn GL, Draper DE. RNA structure. Curr Opin Struct Biol. 1998 Jun;8(3):278-85. doi: 10.1016/s0959-440x(98)80059-6. Review. PubMed PMID: 9666322.
Gyi JI, Lane AN, Conn GL, Brown T. Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes. Biochemistry. 1998 Jan 6;37(1):73-80. doi: 10.1021/bi9719713. PubMed PMID: 9425027.
Bonifacio GF, Brown T, Conn GL, Lane AN. Comparison of the electrophoretic and hydrodynamic properties of DNA and RNA oligonucleotide duplexes. Biophys J. 1997 Sep;73(3):1532-8. doi: 10.1016/S0006-3495(97)78185-2. PubMed PMID: 9284320; PubMed Central PMCID: PMC1181052.
Conte MR, Conn GL, Brown T, Lane AN. Conformational properties and thermodynamics of the RNA duplex r(CGCAAAUUUGCG)2: comparison with the DNA analogue d(CGCAAATTTGCG)2. Nucleic Acids Res. 1997 Jul 1;25(13):2627-34. doi: 10.1093/nar/25.13.2627. PubMed PMID: 9185574; PubMed Central PMCID: PMC146795.
Sutton DH, Conn GL, Brown T, Lane AN. The dependence of DNase I activity on the conformation of oligodeoxynucleotides. Biochem J. 1997 Jan 15;321 ( Pt 2)(Pt 2):481-6. doi: 10.1042/bj3210481. PubMed PMID: 9020884; PubMed Central PMCID: PMC1218094.
Conte MR, Conn GL, Brown T, Lane AN. Hydration of the RNA duplex r(CGCAAAUUUGCG)2 determined by NMR. Nucleic Acids Res. 1996 Oct 1;24(19):3693-9. doi: 10.1093/nar/24.19.3693. PubMed PMID: 8871546; PubMed Central PMCID: PMC146164.
Gyi JI, Conn GL, Lane AN, Brown T. Comparison of the thermodynamic stabilities and solution conformations of DNA.RNA hybrids containing purine-rich and pyrimidine-rich strands with DNA and RNA duplexes. Biochemistry. 1996 Sep 24;35(38):12538-48. doi: 10.1021/bi960948z. PubMed PMID: 8823191.
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