• Dunkle et al., PNAS 2014

  • Hong et al., PNAS 2018

  • Schureck et al., PNAS 2015

  • Hong et al., Structure 2018

  • Ruangprasert et al., Mol Micro 2017

  • Hoffer et al, JBC 2017

Contact

Christine M. Dunham, Ph.D.
Associate Professor
Department of Biochemistry
Emory University School of Medicine
1510 Clifton Rd., Room G223
Atlanta, Georgia 30322

404.712.1756 (office)
404.727.4928 (lab)
404.727.2738 (fax)
christine.m.dunham at emory.edu


My NCBI

Research Gate

RESEARCH INTERESTS

The Dunham laboratory studies the structure and function of bacterial protein synthesis. The ribosome is a large macromolecular machine that produces all proteins in every living organism and is the target for half of all clinical antibiotics. Therefore understanding how the ribosome is regulated is a fundamental question in biology.

We study both the canonical function of the ribosome as well as the regulation of translation that results from stress. Major projects include understanding how the ribosome maintains the three nucleotide genetic code during elongation and how bacteria regulate translation in response to diverse ranges of stress. We use a number of interdisciplinary approaches including structural biology, biochemistry, and molecular biology techniques.

We are always interested in recruiting bright, creative and motivated students and postdoctoral fellows to join our research group. If interested, please click here.

Funding

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Latest News

May 2019: BCDB Graduate Student Jacob Mattingly joins the lab- welcome!

April 2019: Congrats to Pooja for being acknowledged as a NSF GRFP Honorable Mention!

April 2019: We are grateful for receiving the 2018 Cozzarelli Prize from the National Academy of Sciences for the Best Biological Sciences Paper published in 2018!

April 2019: Congrats to Ian for his selection to give a seminar at the 2019 EMBO Toxin-Antitoxin meeting in Windsor, England!

April 2019: Congrats to lab members Eric, Ha An, Ian, Pooja and Kim who presented their research at the ASBMB meeting in Orlando!

February 2019: Congrats to Marc, Jeff, Dongxue and Eric for their paper published in Mol Microbiol! (and we got the cover too!)

February 2019: Congrats to Ha An for her research published in JBC as an Editor’s Selection! (top 2% of papers published) Cool Ha An profile!

December 2018: Chemistry Department graduate student Jiayue Sun joins the lab- welcome!

November 2018: Congrats to Eric for his research published in Nucleic Acids Research in collaboration with the Fredrick lab! (and the cover image too!)

September 2018: Congrats to Sam for his research published in PNAS with a commentary by Prof. John Atkins! More: Emory Lab Land Blog.

July 2018: Congrats to Christine for being selected the 2019 ASBMB Young Investigator!

May 2018: MSP graduate student Pooja Srinivas joins the lab- welcome!

 

 

Research Highlights

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ASBMB Lab
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