Keith D. Wilkinson, Ph.D.
Professor and Associate Chair
Our laboratory concentrates on the regulation of protein amount and location in the cell. We are studying the ubiquitin-dependent proteolysis system that is responsible for regulated degradation of intracellular proteins as well as the role of ubiquitin and ubiquitin-like proteins as a targeting signal.
My research interests are focused on ubiquitin-dependent proteolysis as a regulator of protein homeostasis and its role in formation of prions and other amyloid-like protein aggregates associated with neurodegenerative diseases. My research aimed at studying the involvement of cellular quality control system and actin cytoskeleton in protein aggregation and examining the auxillary proteins mediating environmental and physiological regulation of amyloids, using yeast prions as a model.
I am from Boston, Massachusetts and am currently a junior at Emory University majoring in Biology. My plan is to pursue an MD/PhD program in the future. Aside from academics and research, most of my time is spent working on Emory University’s EMS Unit, serving as president for Emory University’s Global Medical Brigades and being the best intramural basketball player ever! In my three years in the Wilkinson laboratory, I have worked heavily with understanding the roles the amino acids asparagine and glutamine play in prion induction by the prion-inducing protein Lsb2. So far, we have been able to postulate that an increase in asparagine does result in better and more stable prion propagation of Lsb2 in yeast.
Awards and Recognitions: Phi Beta Kappa, Phi Eta Sigma, Deans List all semesters, AP Schoalar with Distinction, GlaxoSmithKline Biomedical Research Fellowship
I grew up in Tucson, Arizona, and am currently a junior at Emory University pursuing a double major in Biology and Philosophy. I joined the K.D. Wilkinson lab in Fall 2014 of my sophomore year. My current project focuses on the regulation of polyglutamine toxicity, specifically Huntington’s Disease, by an actin-associated protein, Lsb2. When I am not in lab, I enjoy knitting, reading, and listening to podcasts.
Yiying Wang, Maggie Mang, Yue Wang, Lijie Wang, Robert Klein, Beihua Kong, Wenxin Zheng: Tubal origin of ovarian endometriosis and clear cell and endometrioid carcinoma. Am J Cancer Res 2015;5(3):869-879.
SIRE Fellow for 2014-2015 academic year
SURE Fellow for Summer 2015
I grew up in Austin, TX. At Emory University I am pursuing B.S. in biology and B.A. in political science. I joined the K. D. Wilkinson Lab in 2014 (my freshman year). My project focuses on elucidating the role of Cdc48 in Lsb2 Degradation. When I am not in lab, I enjoy: running outside, reading literature about American race relations, and immersing myself in my Korean heritage.
Awards and Recognitions:
Emory Liberal Arts Scholar – Academic Years 2014-2018
Dean’s List – Academic Year 2014-15, Fall 2015
Georgia Tech Petit Scholar – Jan-Dec 2016
National Institute of Health/National Cancer Institute Undergraduate Research Fellow – May-Aug 2015
SIRE Research Partners Program – Academic Year 2014-2015
I grew up in New York and New Jersey. At Emory University I am pursuing a B.S. in biology and a minor in global health. I joined the K.D. Wilkinson Lab in 2013 (my freshman year). My project focuses on the analysis of the Ste18 gene in Saccharomyces cerevisiae. This past summer I also did research at UCLA. When I am not in the lab, I enjoy: playing guitar, working out, reading, surfing, spending time with my sorority sisters, and volunteering in Atlanta public schools.
I grew up in Birmingham, Alabama after immigrating to the US from China at a young age. I am currently a senior at Emory University, pursuing a B.S. in Biology from Emory College and a BBA in Finance from Emory’s Goizueta Business School. I joined the K.D. Wilkinson Lab my sophomore year in the fall of 2013. My project focuses on Ste18, the γ-subunit of a G-protein in the S. cerevisiae mating pheromone pathway, and its role in prion induction. When I am not in lab, I enjoy running, football, basketball, and reading.
Awards and Recognitions: National Merit Scholar, Emory Liberal Arts Scholarship, SIRE Undergraduate Research Fellow, Phi Eta Sigma Honor Society, Dean’s List
Summer internship: Amgen – corporate finance intern (summer 2015), returning to work full-time as a financial analyst in summer 2016