Richard A. Kahn, Ph.D.
Professor
We study cell regulation, particularly that involving members of the Arf
family of GTPases. The Arf family is made up of 30 different
genes/proteins in mammals and we study several of them. Currently we
have projects that focus on: (A) Arl2 and Arl3 and their roles in cell
division, cytokinesis, microtubule dynamics, ciliogenesis, mitochondrial
functions, and possible links to cancer therapies, and (B) the role of
Arfs and Arf-dependent coat proteins/complexes in regulating membrane
traffic and specifically the traffic/processing of the Alzheimer’s
precursor protein (APP), BACE, and g-secretase in neuronal cells as
likely to be revealing about Alzheimer’s Disease pathogenesis and
prevention.
Current Members of the Kahn Lab
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Anna Ivanova
Postdoctoral Fellow
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Slee Yi
Research Specialist
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