Publication Years

2009
2008
2006
2005
2004
2003
2002
2001
2000
1999

2009 Publications
Griffiths LM, Swartzlander D, Meadows KL, Wilkinson KD, Corbett AH, Doetsch PW. (2009) Dynamic Compartmentalization of Base Excision Repair Protein in Response to Nuclear and Mitochondrial Oxidative Stress. Mol. Cell Biol. 29(3):794-807.

2008 Publications
Saxowsky TT, Meadows KL, Klungland A, Doetsch PW. (2008) 8-oxoguanine-mediated Transcriptional Mutagenesis casues Ras Activation in Mammalian Cells. Proc. Natl. Acad. Sci. U.S.A. 105: 18877-18882.

Rowe LA, Degtyareva NP, Doetsch PW. (2008) DNA Damage-induced Reactive Oxygen Species (ROS) Stress Response in Saccharomyces cerevisiae. Free Rad. Biol. Med. 45:1167-1177.

Degtyareva, NP, Chen L, Mieczkowski P, Petes TD, Doetsch PW. (2008) Chronic Oxidative DNA Damage Due to DNA Repair Defects Causes Chromosomal Instability in Saccharomyces cerevisiae. Mol. Cell Biol. 28:5432-5445.

Rowe LA, Degtyareva NP, Doetsch PW. (2008) DNA Damage-induced Reactive Oxygen Species (ROS) Stress Response in Saccharomyces cerevisiae. Free Rad. Biol. Med. 2008 July 30. [Epub ahead of print].

Griffiths LM, Doudican NA, Shadel GS & Doetsch PW. (2008) Analysis of Mitochondrial DNA Oxidative Damage and Mutagenesis in Saccharomyces cerevisiae. Mitochondrial DNA : Methods and Protocols (in press).
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2006 Publications
Doetsch PW, Beljanski V, Song B. (2006) The Ultraviolet Damage Endonuclease (UVDE) Protein and Alternative Excision Repair: A Highly Diverse System for Damage Recognition and Processing. In: DNA Damage Recognition. (W. Siede, Y.W. Kow, P.W. Doetsch, eds.) pp. 223-238. Taylor & Francis, New York.

Bregeon D, Doetsch PW. (2006) Assays for Transcriptional Mutagenesis in Active Genes. Methods Enzymol. 409: 345-357.

Saxowsky TT, Doetsch PW. (2006) RNA Polymerase Encounters with DNA Damage: Transcription-Coupled Repair or Transcriptional Mutagenesis? Chem. Rev. 106(2), 474-488.
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2005 Publications
Beljanski V, Villanueva JM, Doetsch PW, Natile G, Marzilli LG. (2005). Marked Dependence on Carrier-Ligand Bulk but Not on Carrier-Ligand Chirality of the Duplex versus Single-Strand Forms of a DNA Oligonucleotide with a Series of G-Pt(II)-G Intrastrand Cross-Links Modeling Cisplatin-DNA Adducts. J Am Chem Soc. 127(45):15833-15842.

O'Rourke T, Doudican NA, Zhang H, Eaton JS, Doetsch PW, Shadel GS. (2005) Differential Involvement of the Related DNA Helicases Pif1p and Rrm3p in mtDNA Point Mutagenesis and Stability. Gene 354:86-92.

Doudican NA, Song B, Shadel GS, Doetsch PW. (2005). Oxidative DNA Damage Causes Mitochondrial Genetic Instability in Saccharomyces cerevisiae. Mol. Cell Biol. 25:5196-5204.
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2004 Publications
Bregeon D, Doetsch PW. (2004). A Reliable Method for Generating Double Stranded DNA Vectors Containing Site Specific Base Modifications. BioTechniques 37: 760-766.

 Salmon TB, Evert BA, Song B, Doetsch PW. (2004). Biological Consequences of Oxidative Stress-Induced DNA Damage in Saccharomyces cerevisiae. Nucleic Acids Res. 32: 3712-3723.

Evert BA, Salmon TB, Song B, Liu JJ, Siede W, Doetsch PW. (2004). Spontaneous DNA Damage in Saccharomyces cerevisiae Elicits Phenotypic Properties Similar to Cancer Cells. J. Biol. Chem. 279: 22585-22594.

 Beljanski V, Marzilli L, Doetsch PW. (2004). DNA Damage Processing Pathways Involved in the Eukaryotic Cellular Response to Anticancer DNA Crosslinking Agents. Mol. Pharm. 65:1496-1506.

 Hanna M, Chow BL, Morey NJ, Jinks-Robertson S, Doetsch PW, Xiao W. (2004). Involvement of Two Endonuclease III Homologs in the Base Excision Repair Pathway for the Processing of DNA Alkylation Damage in Saccharomyces cerevisiae. DNA Repair 3:51-59.
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2003 Publications
Bregeon D, Doddridge Z, You HJ, Weiss B, Doetsch PW. (2003). Transcriptional Mutagenesis Induced by Uracil and 8-oxoguanine in Escherichia coli. Molecular Cell 12:959-970.

Meadows KL, Song B, Doetsch PW. (2003). Characterization of AP Lyase Activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: Implications for Biological Function. Nucleic Acids Res. 31:5560-5567.

Morey NJ, Doetsch PW, Jinks-Robertson S. (2003). Delineating the Requirements for Spontaneous DNA Damage Resistance Pathways in Genome Maintenance and Viability in Saccharomyces cerevisiae. Genetics. 164:443-455.
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2002 Publications
Doetsch PW. (2002). Translesion Synthesis by RNA Polymerases: Occurrence and Biological Implications for Transcriptional Mutagenesis. Mutat. Res. 510:131-140.

O'Rourke TW, Doudican NA, Mackereth MD, Doetsch PW, Shadel GS. (2002). Mitochondrial Dysfunction Due to Oxidative Mitochondrial DNA Damage is Reduced through Cooperative Actions of Diverse Proteins. Mol. Cell. Biol. 22:4086-4093.
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2001 Publications
Xiao W, Chow BL, Hanna M, Doetsch PW. (2001). Deletion of the MAG1 DNA Glycosylase Gene Suppresses Alkylation-Induced Killing and Mutagenesis in Yeast Cells Lacking AP Endonucleases. Mutat. Res. 487:137-147.

Kim J-E, You HJ, Choi J-Y, Doetsch PW, Kim J-S, Chung M-H. (2001). NTG2 of Saccharomyces cerevisiae Repairs the Oxidation Products of 8-Hydroxy Guanine. Biochem. Biophys. Res. Comm. 285:1186-1191.

Doetsch PW. (2001). DNA Repair Disorders. In: Embryonic Encyclopedia of Life Sciences, Nature Publishing Group, London, www.els.net.

Doetsch PW, Morey NJ, Swanson RL, Jinks-Robertson S. (2001). Yeast Base Excision Repair: Interconnections and Networks. Prog. Nucleic Acids Res. Mol. Biol. 68:29-39.

Venhkataraman R, Donald C, Roy R, You HJ, Doetsch PW, Kow YK. (2001). Enzymatic Processing of DNA Containing Tandem Dihydrouracil by Endonucleases III and VIII. Nucleic Acids Res. 29:407-414.
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2000 Publications
Doetsch PW. (2000). DNA Damage, Repair and Mutagenesis (Editorial). Methods 22:115.

You HJ, Viswanathan A, Doetsch PW. (2000). An In vivo Technique for Determining Transcriptional Mutagenesis. Methods 22:120-126.

Alleva JL, Doetsch PW. (2000). The Nature of the 5' Terminus is a Major Determinant for DNA Processing by Schizosaccharomyces pombe Rad2p, a FEN-1 Family Nuclease. Nucleic Acids Res. 28:2893-2901.

Kaur B, Doetsch PW. (2000). Ultraviolet DNA Endonuclease (Uve1p): A Structure and Strand-Specific DNA Endonuclease. Biochemistry 39:5788-5796.

Alleva JL, Hurwitz J, Zuo S, Doetsch PW. (2000) Zuo S, Doetsch PW. (2000). In vitro Reconstitution of the Schizosaccharomyces pombe Alternative Excision Repair Pathway. Biochemistry 39:2659-2666.
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1999 Publications
Villanueva JM, Jia X, Yohannes PG, Doetsch PW, Marzilli LG. (1999). Cisplatin (cis-Pt(NH3)2Cl2) and cis-[Pt(NH3)2(H2O)2]2+ Intrastrand Cross-linking Reactions at the Telomere GGGT DNA Sequence Embedded in a Duplex, a Hairpin, and a Bulged Duplex: Use of Mg2+ and Zn2+ to Convert a Hairpin to a Bulged Duplex. Inorganic Chem. 38:6069-6080.

Villanueva JM, Pohl J, Doetsch PW, Marzilli LG. (199). The Mutagenic Base Damage, 5,6-Dihydrouracil (DHU) Incorporated into a Self-Complementary Duplex: NMR Evidence that DMU is Intrahelical and Causes Minimal Distortion. J. Am. Chem. Soc. 121:10652-10653.

Doetsch PW. (1999). DNA Damage. In: Embryonic Encyclopedia of Life Sciences, Nature Publishing Group, London, www.els.net.

You HJ, Swanson RL, Harrington C, Corbett AH, Senturker S, Jinks-Robertson S, Wallace SS, Boiteux S, Dizdaroglu M, Doetsch PW. (1999). Saccharomyces cerevisiae Ntg1p and Ntg2p: Broad Substrate Specificity N-Glycosylases for the Repair of Oxidative DNA Damage in the Nucleus and Mitochondria. Biochemistry 38:11298-11306.

Viswanathan A, Liu J, Doetsch PW. (1999). E. coli RNA Polymerase Bypass of DNA Base Damage-Mutagenesis at the Level of Transcription. In: Molecular Strategies in Biological Evolution (L.H. Caporale, ed.) Annals, 870:386-388. The New York Academy of Sciences, New York.

Bazar LS, Collier GB, Vanek PG, Silas BA, Kow YW, Doetsch PW, Reeder DJ, Cunningham RP, Chirikjian JG. (1999). Mutation Identification DNA Analysis System (MIDAS) for DNA Mutation Detection. Electrophoresis. 20:1141-1148.

Kaur B, Fraser JL, Freyer GA, Davey S, Doetsch PW. (1999). A Uve1p-mediated Mismatch Repair Pathway in Schizosaccharomyces pombe. Mol. Cell. Biol. 19:4703-4710.

Avery AM, Kaur B, Taylor JS, Mello JA, Essigmann JM, Doetsch PW. (1999). Substrate specificity of Ultraviolet DNA Endonuclease (Uve1p) from Schizosaccharomyces pombe. Nucleic Acids Res. 27:2256-2264.

Viswanathan A, You HJ, Doetsch PW. (1999). Phenotypic Change Caused by Transcriptional Bypass of Uracil in Non-dividing Cells. Science. 284:159-162.

Swanson RL, Morey NJ, Doetsch PW, Jinks-Robertson S. (1999). Overlapping Specificities of Base Excision Repair, Nucleotide Excision Repair, Recombination, and Translesion Synthesis Pathways for DNA Base Damage in Saccharomyces cerevisiae. Mol. Cell. Biol. 19:2929-2935.

Klungland A, Moss H, Gunz D, Constantinou A, Clarkson SG, Doetsch PW, Bolton PH, Wood RD, Lindahl T. (1999). Base Excision - Repair of Oxidative DNA Damage Activated by XPG Protein. Molecular Cell 3:33-42.

Doetsch PW, Viswanathan A, Zhou W, Liu J. (1999). Bypass of DNA Damage by RNA Polymerases: Implications for DNA Repair and Transcriptional Mutagenesis. In: DNA Damage and Repair: Oxygen Radical Effects, Cellular Protection, and Biological Consequences. (M. Diadaroglu and A Karakaya, eds.) pp. 97-110. Kluwer/Plenum, New York.
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