Patrick WM, Matsumura I. 2008. A study in molecular contingency: glutamine phosphoribosylpyrophosphate amidotransferase is a promiscuous and evolvable phosphoribosylanthranilate isomerase. J.Mol.Biol. 377: 323-336. link
Patrick WM, Quandt E, Swartzlander D, Matsumura I. 2007. Multicopy suppression underpins metabolic evolvability. Mol Biol Evol. 24(12): 2716-2722. link
Greene DN, Whitney S, Matsumura I. 2007. Artificially evolved Synechococcus PCC6301 Rubisco variants exhibit improvements in folding and catalytic efficiency. Biochem. J. 404(3):517-24. link
Geddie ML, Matsumura I. 2007. Antibody-induced oligomerization and activation of an engineered reporter enzyme J.Mol.Biol. 369(4):1052-9. link
Polizzi KM, Parikh MR, Spencer CU, Matsumura I, Lee JH, Realff MJ, Bommarius AS. 2006. Pooling for improved screening of combinatorial libraries for directed evolution. Biotechnology Prog. 22(4):961-7.
Parikh MR, Greene DN, Woods KK, Matsumura I. 2006. Directed evolution of RuBisCO hypermorphs through genetic selection in engineered Eschericha coli. Protein Eng Des Sel. 19 (3): 113-9. link
O'Loughlin TL, Greene, DN, Matsumura I. 2006. Diversification and specialization of HIV protease function during in vitro evolution Mol Biol Evol. 23 (4):764-72. . link
O'Loughlin TL, Matsumura I. 2006. HIV protease-activated molecular switches based on beta-glucuronidase and alkaline phosphatase. Comb. Chem. High Throughput Screen 9 (4): 313-20. Geddie ML, O'Loughlin TL, Woods KK, & Matsumura I (2005). Rational design of p53, an instrinsically unstructured protein, for the fabrication of novel molecular sensors. J Biol Chem, 280(42):35641-6
. link
Parikh MR & Matsumura I (2005). Site saturation mutagenesis is more efficient than DNA shuffling for the directed evolution of beta-fucosidasae from beta-galactosidase. J Mol Bio 352, 621-628. link
Matsumura I & Rowe LA. (2005). Whole plasmid mutagenic PCR for directed protein evolution. Biomolecular Engineering 22 (2005) 73–79. link
Polizzi KM, Spencer CU, Dubey A, Matsumura, I, Lee JH, Realff MJ, Bommarius AS. 2005. Pooling for Improving Directed Evolution. J Biomol Screen. 10 (8):856-64.
Geddie ML & Matsumura I. (2004). Rapid evolution of beta-glucuronidase specificity by saturation mutagenesis of an active site loop. J Biol Chem, 279(25), 26462–26468. link
Rowe LA, Geddie ML, Alexander OA, & Matsumura, I. (2003) A comparison of directed evolution approaches using the beta-glucuronidase model system. J Mol Bio 332(4), 851-60. link
Post-doctoral:
Matsumura, I. & Ellington, A. D. (2001c). Mutagenic PCR of protein-coding genes for in vitro evolution. In In vitro mutagenesis protocols (Braman, J., ed.), Vol.182, pages 261-269. Humana Press, Totowa, N.J. link
Matsumura, I., Olsen, M.J., & Ellington, A. D. (2001b). Optimization of heterologous gene expression for in vitro evolution. Biotechniques 30(3): 474-476. link
Matsumura, I. & Ellington, A. D. (2001a). In vitro Evolution of Beta-glucuronidase into a Beta-galactosidase Proceeds Through Non-specific Intermediates. J Mol Biol 305(2), 331-339. link
Matsumura, I. & Ellington, A. D. (1999). In vitro evolution of thermostable p53 variants. Protein Sci 8(4), 731-740. link
Matsumura, I., Wallingford, J. B., Surana, N. K., Vize, P. D. & Ellington, A. D. (1999). Directed evolution of the surface chemistry of the reporter enzyme beta- glucuronidase. Nat Biotechnol 17(7), 696-701. link
Osborne, S. E., Matsumura, I. & Ellington, A. D. (1997). Aptamers as therapeutic and diagnostic reagents: problems and prospects. Curr Opin Chem Biol 1(1), 5-9. link
Matsumura, I. & Ellington, A. D. (1996). DNA shuffling brightens prospects for GFP. Nat Biotechnol 14(3), 366.
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