Pallas Lab - Emory University Medical School
Biochemistry Department
4124/4162 Rollins Research Center
| Office: | (404) 727-5620 |
| Phone: | (404) 727-9882 |
| Fax: | (404) 727-3954 |
- Gentry MS, Li. Y, Wei H, Syed F, Patel S, Hallberg RL, Pallas DC. (2005) A Novel Assay for Protein Phosphatase 2A (PP2A) Complexes In Vivo Reveals Differential Effects of Covalent Modifications on Different S.cerevisiae PP2A Heterotrimers. Eukaryotic Cell. June, in press.
- Moreno, CS, Ramachandran, S, Ashby, DG, Laycock, N, Plattner, C, Chen, W, Hahn, WC, and Pallas, DC. Signaling and Transcriptional Changes Critical for Transformation of Human Cells by SV40 Small Tumor Antigen or PP2A B56gamma Knockdown. Cancer Res. 2004; 64: 6978-6988.
Abstract
- Lu, Q., Pallas, D.C., Surks, H.K., Baur, W.E., Mendelsohn, M.E., and Karas, R.H. Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha. Proc Natl Acad Sci U S A 2004; 101: 17126-17131.
Abstract
- Chen, W, Possemato, R, Campbell, KT, Plattner, CA, Pallas, DC, and Hahn, WC. Identification of specific PP2A complexes involved in human cell transformation. Cancer Cell 2004 5: 127-136.
Abstract
- Shern JF, Sharer JD, Pallas D, Bartolini F, Cowan NJ, Reed MS, Pohl J, Kahn RA. Cytosolic Arl2 is complexed with cofactor D and PP2A. J Biol Chem. 2003 278: 40829-36.
Abstract
- Lu, Q, Surks, HK, Ebling, H, Baur, WE, Brown, D, Pallas, DC, and Karas, RH. Regulation of estrogen receptor alpha-mediated transcription by a direct interaction with protein phosphatase 2A. J Biol Chem. 2003; 278: 4639-45.
Abstract
- Harada, JN, Shevchenko, A, Shevchenko, A, Pallas, DC, and Berk, AJ. Analysis of the Adenovirus E1B-55K-Anchored Proteome Reveals its Link to Ubiquitination Machinery. J. Virol. 2002; 76: 9194-9206.
Abstract
- Moreno, CS, Lane, WS, and Pallas, DC. A Mammalian Homolog of Yeast mob1 is both a Member and a Putative Substrate of Striatin Family-Protein Phosphatase 2A Complexes. J Biol Chem 2001; 276:24253-24260.
Abstract
- Wei H, Ashby DG, Moreno CS, Ogris E, Yeong FM, Corbett AH, Pallas DC. Carboxymethylation of the PP2A Catalytic Subunit in Saccharomyces cerevisiae Is Required for Efficient Interaction with the B-type Subunits Cdc55p and Rts1p. J Biol Chem. 2001 Jan 12;276(2):1570-1577.
Abstract
- Ogris, E, Mudrak, I, Mak, E, Gibson, D, and Pallas, DC. Catalytically Inactive Protein Phosphatase 2A Can Bind to Polyomavirus Middle Tumor Antigen and Support Complex Formation with pp60c-src. J. Virol. 1999 73: p. 7390-7398.
Abstract
- Ogris E. Du X. Nelson KC. Mak EK. Yu XX. Lane WS. Pallas DC. A protein phosphatase methylesterase (PME-1) is one of severalnovel proteins stably associating with two inactive mutants of protein phosphatase 2A. Journal of Biological Chemistry. 274(20):14382-91, 1999 May 14.
Abstract
- Cullere X. Rose P. Thathamangalam U. Chatterjee A. Mullane KP. Pallas DC. Benjamin TL. Roberts TM. Schaffhausen BS. Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteins. Journal of Virology. 72(1):558-63, 1998 Jan.
Abstract
- Ogris E. Gibson DM. Pallas DC. Protein phosphatase 2A subunit assembly: the catalytic subunit carboxy terminus is important forbinding cellular B subunit but not polyomavirus middle tumor antigen. Oncogene. 15(8):911-7, 1997 Aug 18. 97430048
Abstract
- Campbell KS. Auger KR. Hemmings BA. Roberts TM. Pallas DC. Identification of regions in polyomavirus middle T and small t antigens important for association with protein phosphatase 2A. Journal of Virology. 69(6):3721-8, 1995 Jun.
Abstract
- (First three authors contributed equally) Fu H. Xia K. Pallas DC. Cui C. Conroy K. Narsimhan RP. Mamon H. Collier RJ. Roberts TM. Interaction of the protein kinase Raf-1 with 14-3-3 proteins [see comments]. Science. 266(5182):126-9, 1994 Oct 7.
Abstract
- Pallas DC. Fu H. Haehnel LC. Weller W. Collier RJ. Roberts TM. Association of polyomavirus middle tumor antigen with 14-3-3 proteins. Science. 265(5171):535-7, 1994 Jul 22.
Abstract
- Shirra, MK, Zhu, Q, Huang, H-C, Pallas, D., and Hansen, U. One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs. Mol. Cell. Biol. 1994; 14: 5076-5087.
Abstract
- Campbell KS. Ogris E. Burke B. Su W. Auger KR. Druker BJ. Schaffhausen BS. Roberts TM. Pallas DC. Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen. Proceedings of the National Academy of Sciences of the United States of America. 91(14):6344-8, 1994 Jul 5.
Abstract
- Pallas DC. Weller W. Jaspers S. Miller TB. Lane WS. Roberts TM. The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens. Journal of Virology. 66(2):886-93, 1992 Feb.
Abstract
- Kaelin WG Jr. Pallas DC. DeCaprio JA. Kaye FJ. Livingston DM. Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell. 64(3):521-32, 1991 Feb 8.
Abstract
- Pallas DC. Shahrik LK. Martin BL. Jaspers S. Miller TB. Brautigan DL. Roberts TM. Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell. 60(1):167-76, 1990 Jan 12.
Abstract
- Pallas DC. Morgan W. Roberts TM. The cellular proteins which can associate specifically with polyomavirus middle T antigen in human 293 cells include the major human 70-kilodalton heat shock proteins. Journal of Virology. 63(11):4533-9, 1989 Nov.
Abstract
- Kaplan DR. Pallas DC. Morgan W. Schaffhausen B. Roberts TM. Mechanisms of transformation by polyoma virus middle T antigen. [Review] [139 refs] Biochimica et Biophysica Acta. 948(3):345-64, 1989 Feb.
Abstract
- Pallas DC. Cherington V. Morgan W. DeAnda J. Kaplan D. Schaffhausen B. Roberts TM. Cellular proteins that associate with the middle and small T antigens of polyomavirus. Journal of Virology. 62(11):3934-40, 1988 Nov
Abstract
- Morgan WC. Kaplan DR. Pallas DC. Roberts TM. Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: separation of focus formation and soft-agar growth in transformation assays and correlations with kinase activities in vitro. Journal of Virology. 62(9):3407-14, 1988 Sep.
Abstract
- Ramqvist T, Pallas DC, DeAnda J, Ahrlund-Richter L, Roberts TM, Schaffhausen B, Dalianis T. Immunization against the polyoma tumor specific transplantation antigen (TSTA) with polyoma T-antigens. Int J Cancer 1988; 42: 123-128.
Abstract
- Kaplan DR. Whitman M. Schaffhausen B. Pallas DC. White M. Cantley L. Roberts TM. Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell. 50(7):1021-9, 1987 Sep 25.
Abstract
- Pallas DC. Schley C. Mahoney M. Harlow E. Schaffhausen BS. Roberts TM. Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production. Journal of Virology. 60(3):1075-84, 1986 Dec.
Abstract
- Kaplan DK, Whitman M, Schaffhausen B, Raptis L, Garcea RL, Pallas D, Roberts TM, Cantley L. Phosphatidylinositol metabolism and polyoma-mediated transformation. Proc Natl Acad Sci (USA) 1986, 83:3624-3628.
Abstract
- Pallas D, Solomon F. Cytoplasmic microtubule associated proteins: Phosphorylation at novel sites is correlated with their incorporation into assembled microtubules. Cell 1982, 30:407-414.
Abstract
- Duerr A, Pallas D, Solomon F. Molecular analysis of cytoplasmic microtubules in situ: Identification of both widespread and specific proteins. Cell 1981; 24: 203-211.
Abstract