Pallas Lab - Emory University Medical School
Biochemistry Department
4124/4162 Rollins Research Center

Office:(404) 727-5620
Phone:(404) 727-9882
Fax:(404) 727-3954

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David
David C. Pallas
Lab Head
Department of Biochemistry
Emory University School of Medicine
4125 Rollins Research Center 1510 Clifton Rd.
Atlanta, Georgia 30322

Phone: 404-727-5620
Fax: 404-727-3231

Education:

  • 1977 B.S. University of Georgia, Athens, GA (Biochemistry)
  • 1983 Ph.D. Massachusetts Institute of Technology (Biochemistry). Laboratory of Frank Solomon.

Postgraduate Training:

  • 1983-1986 Research Fellow in Cellular and Molecular Biology/Pathology, Dana-Farber Cancer Institute / Harvard Medical School, Boston, MA. Laboratory of Thomas M. Roberts.

Professional Experience & Appointments:

  • 1986-1995 Instructor in Cellular and Molecular Biology/Pathology, Dana-Farber Cancer Institute/Harvard Medical School, Boston, MA.
  • 1995-2001 Assistant Professor of Biochemistry, Emory University School of Medicine, Winship Cancer Center, Emory University.
  • 2001-present Associate Professor of Biochemistry, Emory University School of Medicine, Winship Cancer Center, Emory University.

Steven
Steven Moody
Postdoctoral Fellow
Department of Biochemistry
Emory University School of Medicine
4173 Rollins Research Center 1510 Clifton Rd.
Atlanta, Georgia 30322



Education:

2000:

  • D. Phil. in Molecular Biology & Genetics
    Univesity of York, York, England

1996:

  • B.Sc. (Hons.) Molecular Biology & Genetics
    University of East Anglia
    Norwich, England

Research:
  • Development of novel sphingolipid anti-cancer drugs and investigating the role of Cyclo-oxygenase 2 enzyme in cancer using a Polyoma Virus mouse model system

Research Appointment:

2000-present:

  • Postdoctoral Fellow
    Department of Biochemistry, School of Medicine
    Emory University 1510 Clifton Road
    Rollins Research Center
    Atlanta, GA 30322

Publications:

  • Development of a High Throughput In Vitro PP2A Assay to Screen for Novel Sphingolipid Modulating Compounds. Manuscript in preparation. Steven J. Moody, Dennis Liotta, Alfred A. Merrill, David C. Pallas.
  • Cyclo-oxygenase 2 and Polyoma Virus Induced Tumourigenesis. Manuscript in preparation. Steven J. Moody, Monica J. McQuoid, Pablo Morales, Dirck Dillehay, Aaron Lukacher, David C. Pallas.
  • An Osteosarcoma Mouse model: Polyoma Virus Infection of ?-2 Microglobulin knockout mice. Manuscript in preparation. Steven J. Moody, Monica J. McQuoid, Pablo Morales, Dirck Dillehay, Aaron Lukacher, David C. Pallas

Rick
Yikun Li
Postdoctoral Fellow
Department of Biochemistry
Emory University School of Medicine
4173 Rollins Research Center 1510 Clifton Rd.
Atlanta, Georgia 30322




Education:

09/1999-09/2003:

  • Ph.D. in Cell & Molecular biology
    Department of Cell & Molecular biology
    School of Life Sciences,
    University of Science & Technology of China (USTC)

09/1996-07/1999:

  • M.S. in Molecular Genetics
    School of life sciences,
    SUN YAT-SEN University,
    Guangzhou, P.R.China

09/1992-07/1996:

  • B.S. in Biochemistry
    Anhui University,
    Hefei, Anhui, P.R.China

Research:
  • Investigate the function and regulation of PP2A methylation;
  • Investigate the role of PTPA (rrd1 and rrd2 in Saccharomyces cerevisiae) as a putative PP2A chaperone in Saccharomyces cerevisiae;
  • Distinct P53-independent apoptosis (growth inhibition in Saccharomyces cerevisiae) pathway induced by adenovirus early region 4 transcription unit (E4orf4)

Research Appointment:

12/2003-present:

  • Postdoctoral Fellow
    Department of Biochemistry, School of Medicine
    Emory University 1510 Clifton Road
    Rollins Research Center
    Atlanta, GA 30322

Publications:

  • Zhou Z, Song X, Li Y, & Gong W. Unique Structural Characteristics of Peptide Deformylase from Pathogenic Bacterium Leptospira interrogans. J Mol Biol. 2004 21;339(1):207-15.

Johnthan
Johnthan Gordon
Postdoctoral Fellow
Department of Biochemistry
Emory University School of Medicine
4162 Rollins Research Center 1510 Clifton Rd.
Atlanta, Georgia 30322




Education:

  • B.S. University of South Carolina, Aiken, SC (Biology)
  • Ph.D. Medical University of South Carolina (Molecular Biology/Biochemistry).

Postgraduate Training:

  • 2000-2001: Dr. Donald Burke. Chemistry, Indiana University - Invivo screening RNA optamers against HIV-1 reverse transcriptase.
  • 2001-2003: Dr. John Foley, Medical Sciences, Indiana University - Studying PTHP's role in metastasis in breast cancer.
  • 2003-Present Dr. David Pallas, Biochemistry, Emory University School of Medicine - Studying structure/function of striatin and its interaction with estrogen receptors.

Research:

  • Analysis of straitin : estrogen receptor interaction.
  • Structure/function studies of striatin.
  • Effects of polyomavirus small T and middle T antigens on the function of straitin.

Publications:

  • Phillips CA, Gordon J, and Spicer EC "Backeriophage T4 RegA Protein Binds RNA as a Monomer Overcoming Dimer Interactions." NAR (1996) 24(21): 4319-4326.
  • Gordon J, Sengupta T, Phillips CA, O'Malley S, Williams KR, and Spicer EK, "Identification of the RNA Bind Domain of T4 RegA Protein by Structure-based Mutagenesis." JBC (1999). 274: 32265-32273.
  • Sengupta T, Gordon J, and Spicer ER, "RegA Proteins from Phage T4 and R869 Have Conserved Helix-Loop-Groore-RNA-binding Motifs by Different RNA-Binding-Specificities." NAR (204) 29(5): 1175-1184.

Fellowships:

  • 2003-Present FIRST fellowship

Courtney
Courtney Plattner
Lead Technician
Department of Biochemistry
Emory University School of Medicine
4173 Rollins Research Center 1510 Clifton Rd.
Atlanta, Georgia 30322




Education:
  • Emory University (Atlanta, GA) B.A. in Italian Studies in 1998-2002

Undergraduate Research Experience:

  • 1999 - 2002: Department of Dermatology
Publications
  • Chen, W., R. Possemato, et al. (2004). "Identification of specific PP2A complexes involved in human cell transformation." Cancer Cell 5(2): 127-36.

Mari Bales
Workstudy Student
Kenneth Keegan
Workstudy Student
Ilona Kichko
Workstudy Student
Elina Levin
Workstudy Student
Bruce Smith
Workstudy Student